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18 Headlines Israel Researchers at Tel AvivUniversity have 3D-printed a glioblastoma tumour, whichmimics themalignancy of a living cancer. This first-of-its-kindmodel, which includes both cancer tissue and the surrounding environment that affects the tumour’s development, will enable potential treatments to be better tested, improving and accelerating the development of drugs for this type of cancer. UK Anewgene therapy that could protect against life-limiting diseases such as cancer and dementia has been discovered by scientists at the University of Sheffield. The research involves three proteins, USP11, KEAP1, andSETX, whichwork together to repair DNAdamage. Understanding the role these proteins play in protecting cells fromDNAdamagewill helpmake it possible for scientists to target these proteins tomodify their behaviour, promoting genome and cell health and preventing diseases. Research led by the University of Bristol has identified new targets for memory enhancing drugs. Currently, there are limited treatments for memory loss. The discovery of new targets could lead to the development of treatments for a variety of brain disorders that involve memory loss, including Alzheimer’s disease and schizophrenia. Neurological research from around the globe USA Researchers at the University of California San Francisco Parnassus Campus have translated hundreds of brain wave recordings into a 3D movie showing where seizures start and how they spread through the brain. This personalised visualisation of seizure activity makes it easy to define where a seizure starts, whether there is one or more trigger sites, and how it spreads. Combining neuroimaging and artificial intelligence, a research team led by the University of Texas Southwestern Medical Centre, has identified novel brain signatures unique to the response of each antidepressant. These new biomarkers could spare patients suffering severe side effects two to threemonths of taking the wrongmedication.

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